According to officials, the crash last night sparked blazes on the ground that left burned-out buildings and vehicles in their wake.
The Federal Aviation Administration, FAA, confirmed that six people were on the Learjet aircraft, but no one has confirmed whether there were any survivors.
The aircraft, which the FAA said was a Learjet 55 executive aircraft with two people aboard, crashed into a densely-populated district of the city with homes, shops, and busy roads.
The FAA said in a statement confirming that it would investigate along with the National Transportation Safety Board, it was bound for Springfield-Branson National Airport in Missouri, and had taken off from Northeast Philadelphia Airport.
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Meanwhile, US Transportation Secretary, Sean Duffy, said there were reportedly six people aboard the plane but no immediate confirmation of casualties was stated.
Pennsylvania Governor, Josh Shapiro wrote on X, that they are offering all resources as emergency services to respond to the small private plane crash in Northeast Philly.
The crash in the east coast US city came just two days after a passenger jet and military helicopter collided off Washington’s Reagan National Airport, killing 67 people in the deadliest US air disaster in almost a quarter century.
The Learjet that crashed was an aircraft used to transport medical patients, according to flight tracking site FlightAware.
Philadelphia’s Office of Emergency Management wrote on X that there was a major incident underway and that roads in the vicinity were closed, calling on the public to avoid the area.
Dozens of first responders were outside Roosevelt Mall, a strip mall with retailers and food outlets.