The crash, which occurred earlier in the day, involved a trailer carrying containers that fell, narrowing the lanes and creating significant traffic gridlock.
The FRSC Lagos Sector Commander, Kehinde Hamzat, in a statement urged motorists to remain calm and avoid actions that could aggravate the situation.
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It noted that some impatient drivers worsened the situation by driving against traffic flow on the Lagos-bound side of the road, further disrupting traffic in both directions.
The FRSC said it is working alongside the police, LASTMA, and other traffic management agencies to clear the fallen trailer and restore normal traffic flow.